What Are the Uses and Structure of High-Grade Tert-Butylamine (CAS 75-64-9)?

Tertiary Butylamine, often referred to as TB Amine, is a widely used organic intermediate in industrial chemistry. Officially listed as Tert-butylamine CAS 75-64-9, it is supplied as a clear, colourless liquid with a strong amine-like smell. 

What makes this molecule useful is its compact and branched structure. This allows it to react easily with other compounds, which is why Tert-butylamine uses are spread across pharmaceuticals, agrochemicals, and specialty chemical manufacturing. 

In this blog, we break down what tert-butylamine is, explain its structure in simple terms, outline its key properties, describe how it is manufactured, and explore where it is commonly used in industry. 

Tertiary Butylamine: Quick Facts (CAS 75-64-9) 

Before looking at applications, it helps to understand the basic profile of Tertiary Butylamine. 

• Product name: Tertiary Butylamine (TB Amine) 

• IUPAC name: 2-Methylpropan-2-amine 

• CAS number: 75-64-9 

• Molecular formula: C₄H₁₁N 

• Molecular weight: 73.139 g/mol 

• Boiling point: 43–47°C 

• Melting point: −67.50°C 

• Density: 0.696 g/mL 

• Vapour density: 2.5 (Air = 1) 

• Appearance: Clear, colourless liquid 

It is classified as a flammable liquid and typically has a shelf life of 24 months when stored in sealed drums at room temperature. These properties explain why TB Amine is handled with care, but is still suitable for large-scale industrial operations. 

Tert-Butylamine Structure Explained in Simple Terms 

The Tert-butylamine structure consists of a compact, branched carbon group attached to an amine (nitrogen-containing) functional group. The “tert-butyl” portion refers to a tightly packed group of four carbon atoms, while the amine group is responsible for its chemical reactivity. 

This structure plays a big role in how the compound behaves. The branching keeps the molecule compact, which contributes to its relatively low boiling point and predictable reaction behaviour. Because of this, tert-butylamine works well in processes that require controlled reactions rather than aggressive or unstable chemistry. 

You may also see this compound listed under names such as t-Butylamine, TB Amine, 2-Amino-2-methylpropane, or 2-Aminoisobutane. All of these refer to the same chemical structure. 

Solubility and Handling: What Buyers Should Know 

One reason tert-butylamine is easy to work with is its solubility. It mixes well with water, alcohols, and ether, and is also soluble in chloroform. This flexibility allows it to be used across different reaction environments without major formulation changes. 

From a handling point of view, TB Amine is treated like most amine-based industrial chemicals. It is flammable, so standard safety procedures apply. When stored properly in closed containers at room temperature, it remains stable throughout its stated shelf life. For plants already equipped to handle organic intermediates, tert-butylamine fits smoothly into existing systems. 

How Is Tert-Butylamine Manufactured? 

On an industrial scale, tert-butylamine is most commonly produced by the direct amination of isobutylene. This route is widely used because it allows consistent production and is suitable for commercial volumes. 

There are also alternative methods, such as the hydrogenolysis of 2,2-dimethylethylenimine or processes involving tertiary butylformamide followed by hydrolysis. These routes are less common but still used in specific settings. 

For end users, the manufacturing route matters mainly because it affects consistency. Stable composition and predictable properties are especially important when the material is used in sensitive downstream synthesis. 

Tert-Butylamine Uses Across Industries 

The real value of TB Amine lies in its role as an intermediate rather than a finished product. Common Tert-butylamine uses include: 

• Pharmaceutical industry: Used as a building block in pharmaceutical-oriented chemical synthesis where controlled reactivity is essential. 

• Agrochemical sector: Supplied as an intermediate in crop protection and agricultural chemistry supply chains. 

• Specialty chemical manufacturing: Used to produce other organic intermediates that require branched amine inputs. 

• Automobile and allied industries: Part of broader chemical value chains that support automotive and industrial manufacturing. 

Across these sectors, tert-butylamine is chosen for its reliability and compatibility with multiple synthesis pathways. 

What “High-Grade” Tert-Butylamine Means in Practice 

When buyers look for High-grade Tert-butylamine CAS 75-64-9, they are usually focused on consistency, documentation, and dependable supply rather than just a purity number on paper. 

Thus, a buyer can verify the actual product by reading its certificate of analysis, then check that the physical properties (boiling point, density, etc.) match their requirements, as well as verify the manufacturer’s conditions for both packaging and storage of the product. Verifying all of the above items helps create an uninterrupted stream of production and minimize variations in downstream processing. 

Vinati Organics manufactures high-grade tert-butylamine for pharmaceutical, chemical, automobile, and agrochemical applications, serving both domestic and international markets with specification-driven supply. 

A Practical Intermediate for Real-World Manufacturing 

Tertiary butylamine is composed of a branched, compact configuration that exhibits good solubility and ease of use. Because of these properties, tert-butylamine CAS 75-64-9 is a reliable source for manufacturers seeking consistent performance, process stability, and predictable results from their materials. 

Vinati Organics is committed to providing high-quality tertiary butylamine tailored to our customers’ actual manufacturing needs. You can access a variety of specifications, packaging specifications and technical documentation to determine the proper form of tertiary butylamine for their specific manufacturing processes.