4-Methoxy Acetophenone (CAS – 100-06-1)

Overview of 4-Methoxy Acetophenone

4-Methoxy Acetophenone, also known as p-methoxy acetophenone, is an organic compound with the chemical formula C₉H₁₀O₂. It appears to be a white to pale yellow crystalline solid with a mild, characteristic odor. This compound is an essential intermediate in producing various specialty chemicals, pharmaceuticals, and UV-absorbing agents.

With a CAS number 100-06-1, 4-methoxy Acetophenone is widely utilized in industries where photostability and controlled reactivity are crucial. One of its most significant applications is synthesizing Avobenzone, a UVA-blocking agent widely used in sunscreen formulations. Its unique chemical structure enables it to function as a precursor for numerous organic compounds, ensuring consistency and efficiency in chemical manufacturing.

• Chemical Name: 4-Methoxy Acetophenone
• CAS Number: 100-06-1
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.17 g/mol
• Appearance: White to off-white crystalline solid
• Odor: Mild aromatic odor
• Solubility: Soluble in ethanol, ether, and slightly soluble in water
• Melting Point: 36-38°C
• Boiling Point: 248°C
• Stability: Stable under normal conditions; avoid exposure to strong oxidizers and light
• Synonyms: p-Methoxyacetophenone, 4-Methoxyphenyl Methyl Ketone

Key Properties

• Fragrance and Flavor Applications:
  Used in the production of perfumes, flavoring agents, and cosmetic formulations.




• Pharmaceutical Intermediate:
  Acts as a key intermediate in the synthesis of pharmaceutical compounds.




• UV Absorption:
  Exhibits strong UV absorption, making it useful in certain industrial and chemical applications.




• Chemical Reactivity:
  Used in organic synthesis due to its functional ketone group.




• Thermal Stability:
  Maintains stability under moderate temperatures but requires proper storage to prevent degradation.

Applications of 4-Methoxy Acetophenone (CAS – 100-06-1)

4-Methoxy Acetophenone (CAS – 100-06-1) is a highly valuable compound across various industrial applications. Its primary uses include:

• Intermediate in UV-blocking agent Synthesis:
  One key application of 4-Methoxy Acetophenone (CAS – 100-06-1) is its role as a raw material in synthesizing Avobenzone, a highly effective UVA absorber in sunscreen formulations. Its controlled chemical properties contribute to the efficient production of stable and photoprotective agents, ensuring enhanced skin protection against harmful UV radiation.




• Precursor for Pharmaceuticals:
  As a crucial intermediate in pharmaceutical synthesis, 4-Methoxy Acetophenone is used to develop a variety of active pharmaceutical ingredients (APIs). Its stable molecular structure allows for precise modifications, aiding in producing analgesics, anti-inflammatory drugs, and other medicinal compounds.




• Fragrance and Flavoring Agent:
  Due to its mild, pleasant aroma, 4-Methoxy Acetophenone (CAS – 100-06-1) finds application in the fragrance and flavoring industry. It is commonly used as a component in perfumes, soaps, and cosmetic formulations, contributing to their aromatic stability and longevity.




• Specialty Chemicals and Agrochemicals:
  4-Methoxy Acetophenone is also used to synthesize various specialty chemicals and agrochemicals, which are vital in developing pesticides, herbicides, and plant growth regulators. Its compatibility with numerous chemical reactions ensures efficiency in agricultural formulations.




• Photo stabilizer in Industrial Applications:
  With its chemical stability and controlled reactivity, 4-Methoxy Acetophenone (CAS 100-06-1) is used as a photo stabilizer in certain industrial coatings and polymers. It helps enhance materials’ UV resistance, extending their durability and performance in outdoor environments.

Benefits of Using 4-Methoxy Acetophenone (CAS – 100-06-1)

4-Methoxy Acetophenone provides several advantages that make it a preferred compound in multiple industries. Key benefits include:

• Essential in UV-Blocking Formulations:
  As a crucial precursor for Avobenzone, 4-Methoxy Acetophenone (CAS – 100-06-1) ensures high-quality and effective UVA protection in sunscreen products.




• High Chemical Stability:
  The compound’s stable molecular structure enables reliable performance in chemical synthesis, ensuring efficiency in pharmaceuticals, cosmetics, and industrial applications.




• Versatile Industrial Applications:
  4-Methoxy Acetophenone is widely used in pharmaceuticals, personal care, agrochemicals, and industrial formulations, making it an asset for manufacturers.




• Photostability for Long-Term Use:
  Its ability to act as a photo stabilizer helps prevent the degradation of various formulations exposed to UV radiation, ensuring long-term performance and safety.




• Cost-Effective and High-Purity Compound:
  Due to its high efficiency in chemical synthesis, 4-Methoxy Acetophenone minimizes material loss, production waste, and overall operational costs.

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