Anisole (CAS – 100-66-3)

Overview of Anisole

Anisole, known as methoxybenzene, is an organic compound with the chemical formula C₇H₈O. It is a clear, colorless liquid with a mild aromatic odor. Primarily used as an intermediate in the synthesis of specialty chemicals, Anisole (CAS—100-66-3) is also a valuable ingredient in perfumery formulations.

With a CAS number of 100-66-3, Anisole is widely utilized in industries requiring high-purity solvents, stabilizers, and intermediates. Due to its excellent chemical properties, it is a key raw material for producing fragrances, pharmaceuticals, and agrochemicals.

General Information

• Chemical Name: Anisole
• CAS Number: 100-66-3
• Molecular Formula: C₇H₈O
• Molecular Weight: 108.14 g/mol
• Appearance: Colorless liquid
• Odor: Pleasant, sweet aromatic odor
• Solubility: Slightly soluble in water, soluble in ethanol and ether
• Melting Point: -37°C
• Boiling Point: 154°C
• Stability: Stable under normal conditions; avoid exposure to strong oxidizing agents
• Synonyms: Methoxybenzene, Methyl Phenyl Ether

Key Properties

• Solvent Properties: Used as a solvent in organic synthesis and industrial applications.
• Precursor in Synthesis: An essential intermediate in the production of perfumes, pharmaceuticals, and agrochemicals.
• Aromatic Stability: Features a stable benzene ring, making it useful in specialized chemical applications.
• Low Reactivity: Less reactive under standard conditions, providing safe handling and stability.
• Industrial Use: Commonly used in fragrance formulations and as a starting material for complex chemical reactions.

Applications of Anisole (CAS – 100-66-3)

Anisole (CAS – 100-66-3) is a versatile compound with applications across multiple industries. Its primary uses include:

• Perfumery Ingredient
  Due to its pleasant, mild aroma, anisole is extensively used in the fragrance and perfume industry. It acts as a building block for various aroma chemicals, contributing to perfumes’ floral, spicy, and sweet notes. The presence of Anisole in formulations enhances the longevity and depth of scents, making it an essential raw material for high-quality perfumes and personal care products.




• Intermediate in Chemical Synthesis
  Anisole (CAS – 100-66-3) is a crucial intermediate in synthesizing various specialty chemicals. It is used to produce pharmaceuticals, agrochemicals, and fine chemicals. The chemical reactivity of Anisole allows it to participate in numerous organic reactions, including methylation, oxidation, and electrophilic aromatic substitution, enabling the development of complex compounds for industrial applications.




• Precursor in Pharmaceutical Manufacturing
  In the pharmaceutical industry, anisole plays a vital role as a precursor for the synthesizing of active pharmaceutical ingredients (APIs). Its stable molecular structure makes it an excellent choice for drug formulation and production, enhancing the purity and effectiveness of medicinal compounds.




• Usage in Agrochemicals
  Anisole (CAS – 100-66-3) is employed in formulating agrochemicals, including pesticides, herbicides, and fungicides. It acts as a stabilizer and reaction intermediate, ensuring the efficiency and stability of agricultural products. Its chemical properties contribute to the controlled release of active ingredients in crop protection formulations.




• Solvent in Industrial Applications
  Due to its high solvency and stability, Anisole is used as a solvent in industrial applications, including coatings, adhesives, and chemical processing. It is an effective medium for dissolving and stabilizing various compounds, providing consistency and uniformity in industrial formulations.

Benefits of Using Anisole (CAS – 100-66-3)

Anisole provides several advantages across various industries. The key benefits include:

• Highly Versatile Compound:
  Anisole (CAS 100-66-3) is an essential raw material in the fragrance, pharmaceutical, and chemical industries, offering broad application potential.




• Chemical Stability:
  Its high stability under different conditions makes it a reliable ingredient in chemical synthesis and industrial applications.




• Superior Solvent Properties:
  Anisole is an effective solvent for numerous chemical reactions, aiding in efficient production processes and improving formulation stability.




• Cost-Effective Solution:
  It provides high performance at low concentrations, reducing operational costs associated with material consumption and waste management.




• Eco-Friendly Characteristics:
  Anisole’s controlled usage in formulations contributes to environmentally friendly manufacturing processes, minimizing harmful emissions and waste.

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