A Widely Used Antioxidant 1010: Application, Synthesis & Safety

Posted on: January 9, 2024

Antioxidant 1010, a widely used synthetic antioxidant, plays a crucial role in various industries, safeguarding products from oxidative degradation. This blog looks into the applications, synthesis methods, and safety considerations of Antioxidant 1010, shedding light on its significance in preserving the quality and longevity of diverse materials. 


Applications of Antioxidant 1010: 

  1. Polymer Stabilization:
     One of the primary applications of Antioxidant 1010 lies in polymer stabilization. It is commonly employed in producing plastics, rubbers, and other polymeric materials. By inhibiting the oxidative degradation of polymers, this antioxidant extends the lifespan of products, maintaining their structural integrity and performance. 
  2. Lubricant and Oil Additive:
     Antioxidant 1010 is frequently utilized as an additive in lubricants and oils. Its ability to avoid making free radicals and oxidative by-products enhances the stability of these substances, ensuring that they withstand the challenges posed by heat, air, and other environmental factors. 
  3. Paints And Coatings
     Antioxidant 1010 serves as an additive in coatings and paints, safeguarding against oxidative degradation to preserve the visual appeal and structural integrity of coated surfaces over an extended period. 
  4. Adhesives and Sealants:
     In the adhesives and sealants industry, Antioxidant 1010 serves as a stabilizing agent. It mitigates the impact of oxidative reactions, preventing the degradation of adhesives and sealants over time. It is particularly crucial in applications where durability and longevity are paramount. 
  5. Cosmetics and Personal Care Products:
     This antioxidant finds its way into cosmetics and personal care products, contributing to the preservation of formulations. It hinders the oxidation of ingredients, maintaining the efficacy and stability of skincare, haircare, and beauty products. 
  6. Manufacturing of Rubber:
    Antioxidant 1010 plays a crucial role in safeguarding rubber products from degradation, ensuring they retain their elasticity and resilience, even in demanding conditions within the rubber industry. 


Synthesis of Antioxidant 1010: 

The synthesis of Antioxidant 1010 (6683-19-8) involves a series of chemical reactions, resulting in a compound known as tetrakis[methylene(3,5-di-tert-butyl-4-hydroxyhydrocinnamate)] methane. Here’s a simplified overview of the synthesis process: 

Starting Materials: 

The synthesis begins with the reaction of p-hydroxybenzoic acid and isobutylene to form 3,5-di-tert-butyl-4-hydroxybenzoic acid. 


The obtained acid is then esterified with methanol to produce the corresponding methyl ester. 


Hydrolysis of the methyl ester yields 3,5-di-tert-butyl-4-hydroxybenzoic acid once again. 


The final step involves the condensation of four moles of the hydroxybenzoic acid with formaldehyde, leading to the formation of Antioxidant 1010 (6683-19-8). 

This synthesis pathway results in a highly stable antioxidant with a molecular structure designed to quench free radicals and inhibit oxidation processes efficiently. 

Safety Considerations: 

While Antioxidant 1010 is generally considered safe for its intended applications, it’s essential to consider safety aspects, especially during handling and manufacturing processes. Here are key safety considerations: 

Exposure Limits: 

Workers synthesizing or handling the hindered phenol should adhere to recommended exposure limits. It may include wearing protective equipment such as gloves and goggles to minimize direct skin contact and prevent eye irritation. 


Adequate ventilation in workspaces is crucial to mitigate the risk of inhalation exposure. Proper ventilation systems should be in place to ensure a safe working environment, especially in enclosed spaces where the compound is handled or processed. 

Storage and Handling: 

Antioxidant 1010 should be stored in a cool, dry area away from direct sunlight and incompatible materials. Handling should be done carefully, and spills should be promptly cleaned using appropriate procedures. 

Regulatory Compliance: 

Ensure compliance with local and international regulations regarding the use, handling, and disposal of Antioxidant 1010. It includes the following guidelines set by regulatory entities like the Occupational Safety and Health Administration (OSHA) and the European Chemicals Agency (ECHA). 

Antioxidant 1010 is a pivotal component in preserving the integrity and longevity of materials across diverse industries. As a hindered phenol, its applications in polymer stabilization, lubricants, food packaging, and more underscore its versatility. Understanding the synthesis process and prioritizing safety considerations are paramount for harnessing the benefits of Antioxidant 1010 while ensuring responsible and secure usage in various industrial applications.  

Vinati Organics, a prominent manufacturer of organic chemical products in India, is proud to provide antioxidant 1010 of exceptional quality, setting a benchmark on the global stage. As a pioneer in manufacturing innovative chemical compounds, Vinati Organics plays a crucial role in contributing to various industries globally. The focus on excellence and the establishment of a global reputation for top-quality and highly effective products showcase the company’s dedication to meeting the diverse needs of its customers. For more details on technical specifications and our products get in touch with us.